PKA C-alpha/PKA C-beta polyclonal (N-term), anti-human, mouse
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In stock
SKU
AC-AP7013a
Catalog Number: AC-AP7013a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1034
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1034
Applications: IHC-P, WB
Datasheet
Request Information
Background:
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by the PRKACA gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.
Other Names:
cAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha, PRKACA, PKACA
Target/Specificity:
This PKAC alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human PRKACA.
Antigen Region:
9-40
Antigen Type: Synthetic Peptide
Gene Name: PRKACA
Gene ID: 5566
Primary Accession: P17612
NCBI Accession: NP_002721.1;NP_997401.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by the PRKACA gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.
Other Names:
cAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha, PRKACA, PKACA
Target/Specificity:
This PKAC alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human PRKACA.
Antigen Region:
9-40
Antigen Type: Synthetic Peptide
Gene Name: PRKACA
Gene ID: 5566
Primary Accession: P17612
NCBI Accession: NP_002721.1;NP_997401.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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