PKAalpha+beta polyclonal, anti-human, mouse, rat

Background:
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis.

Synonyms: PPKACA, PKACA, PPNAD4, PKA C-alph

Cellular Location: Cell membrane Cell projection Cilium Cytoplasm Cytoplasmic vesicle Flagellum Mitochondrion Nucleus Mitochondrion Nucleus

Immunogen:
A synthetic peptide of human PKAalpha+beta

Gene Symbol: PKAalpha+beta

Gene ID: 5566

Swiss prot: P17612

Calculated MW: 41kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.