PKC alpha polyclonal, anti-human, mouse, rat

Protein Family: Protein Kinases

Pathway and Disease: Signal Transduction, Cell Communication, Immune System, Endocrine System, Cancers, Infectious Diseases, Nervous and Sensory Systems

Description:
Protein kinase C alpha type (PKC alpha) is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. PKC alpha plays a role in cell motility by phosphorylating CSPG4. PKC alpha is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC alpha also serves as the receptor for phorbol esters, a class of tumor promoters.

Alternate Names: PKC alpha, Protein kinase C alpha type, PKC-alpha, PKC-A, PRKCA, PKCA, PRKACA

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P17252

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PKC alpha.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.