PKC alpha polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Protein kinase C(PKC) is the major phorbol ester receptor. Activation of PKC by calcium ions and the second messenger diacylglycerol is though to play a central role in the induction of cellular responses to a variety of ligand-receptor systems and in the regulation of cellular responsiveness to external stimuli. Three of these, termed alpha, beta and gamma, are highly homologous. PRKCA1 is mapped to 17q22-q23.2. PKC-alpha regulates cardiac contractility and propensity toward heart failure.

Description:
Rabbit IgG polyclonal antibody for Protein kinase C alpha type (PRKCA) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
AAG6 antibody, Aging associated gene 6 antibody, KPCA_HUMAN antibody, MGC129900 antibody, MGC129901 antibody, PICK 1 antibody, PKC A antibody, PKC alpha antibody, PKC alpha antibody, PKC-A antibody, PKC-alpha antibody, PKCA antibody, PRKACA antibody, PRKC A antibody, PRKCA antibody, Protein Kinase C alpha antibody, Protein kinase C alpha type antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminal of human PKC alpha, identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.