PKC alpha polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Protein kinase C (PKC) is the major phorbol ester receptor. Activation of PKC by calcium ions and the second messenger diacylglycerol is thought to play a central role in the induction of cellular responses to a variety of ligand-receptor systems and in the regulation of cellular responsiveness to external stimuli. Three of these, termed alpha, beta and gamma, are highly homologous. PRKCA1 is mapped to 17q22-q23.2. PRKCA1 regulates cardiac contractility and propensity toward heart failure.

Description:
Rabbit IgG polyclonal antibody for Protein kinase C alpha type (PRKCA) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
AAG6 antibody, Aging associated gene 6 antibody, aPKC antibody, KPCA_HUMAN antibody, MGC129900 antibody, MGC129901 antibody, PICK 1 antibody, PKC A antibody, PKC alpha antibody, PKC-A antibody, PKC-alpha antibody, PKCA antibody, PRKACA antibody, PRKC A antibody, PRKCA antibody, Protein Kinase C alpha antibody, Protein kinase C alpha type antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PKC alpha recombinant protein (Position: M153-L342). Human PKC alpha shares 97% and 99% amino acid (aa) sequence identity with mouse and rat PKC alpha, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.