PKC beta 1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that PRKCB activated by oxidative conditions in the cell, induces phosphorylation of p66(SHC) and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase PIN1.

Description:
Rabbit IgG polyclonal antibody for Protein kinase C beta type (PRKCB) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
KPCB_HUMAN antibody, MGC41878 antibody, PKC B antibody, PKC beta antibody, PKC-B antibody, PKC-beta antibody, PKCB antibody, PRKC B antibody, PRKC B1 antibody, PRKCB antibody, PRKCB I antibody, PRKCB1 antibody, PRKCB2 antibody, Protein kinase C beta 1 antibody, Protein kinase C beta antibody, Protein kinase C beta type antibody, protein kinase C, beta 1 polypeptide antibody, protein kinase C, beta-1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PKC beta 1 recombinant protein (Position: E542-V671). Human PKC beta 1 shares 100% amino acid (aa) sequence identity with both mouse and rat PKC beta 1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.