PKC zeta polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP7028a
Catalog Number: AC-AP7028a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01027
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01027
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a constitutive kinase activity which is independent of calcium, and PKC activators, phosphatidylserine and diacylglycerol. Furthermore, it is insensitive to PKC inhibitors and cannot be activated by phorbol ester. The structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.
Other Names:
Protein kinase C zeta type, nPKC-zeta, PRKCZ, PKC2
Target/Specificity:
This PKC zeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the N-terminal region of human PKC zeta.
Antigen Region:
166-197
Antigen Type: Synthetic Peptide
Gene Name: PRKCZ
Gene ID: 5590
Primary Accession: Q05513
NCBI Accession: NP_001028753.1;NP_001028754.1;NP_001229803.1;NP_002735.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a constitutive kinase activity which is independent of calcium, and PKC activators, phosphatidylserine and diacylglycerol. Furthermore, it is insensitive to PKC inhibitors and cannot be activated by phorbol ester. The structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.
Other Names:
Protein kinase C zeta type, nPKC-zeta, PRKCZ, PKC2
Target/Specificity:
This PKC zeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the N-terminal region of human PKC zeta.
Antigen Region:
166-197
Antigen Type: Synthetic Peptide
Gene Name: PRKCZ
Gene ID: 5590
Primary Accession: Q05513
NCBI Accession: NP_001028753.1;NP_001028754.1;NP_001229803.1;NP_002735.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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