PKD1 Polyclonal Antibody

Background:
This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1).

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Autosomal dominant polycystic kidney disease 1 protein, Autosomal dominant polycystic kidney disease protein 1, nPKC-D1, nPKC-mu, OTTHUMP00000208669, OTTHUMP00000208670, PBP, Pc-1, PKD, Pkd1, PKD1, Polycystic Kidney Disease 1, polycystic kidney disease-associated protein, Polycystin 1 Precursor, Polycystin-1, Protein kinase C mu type, Protein kinase D, Serine/threonine-protein kinase D1, transient receptor potential cation channel, subfamily P, member 1, TRPP1

Immunogen: Synthetic peptide of human PKD1

Swissprot: P98161
Gene Accession: NP_001009944

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-10371/sc-10372/sc-10370/sc-25570