PKM2 (clone 1A7-G6-H6), anti-human, mouse, rat, monkey

Background:
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

Synonyms: CTHBP, HEL-S-30, OIP3, PK3, PKM2, TCB, THBP1

Cellular Location: Cytoplasm Nucleus

Immunogen:
Purified recombinant human PKM2 protein fragments expressed in E.coli.

Gene Symbol: PKM2

Gene ID: 5315

Swiss prot: P14618

Calculated MW: 60kDa

Recommended dilution:
WB 1:1000, ICC 1:400,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.