PKM2 (N-term E131) polyclonal, anti-human
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In stock
SKU
AC-AP9076a
Catalog Number: AC-AP9076a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15338
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15338
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
PKM2 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Other Names:
Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3, PKM2
Target/Specificity:
This PKM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the N-terminal region of human PKM2.
Antigen Region:
116-145
Antigen Type: Synthetic Peptide
Gene Name: PKM
Gene ID: 5315
Primary Accession: P14618
NCBI Accession: NP_001193725.1;NP_001193726.1;NP_001193727.1;NP_001193728.1;NP_002645.3;NP_872270.1;NP_872271.1
Other Accession: P11980; P11974; P52480
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
PKM2 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Other Names:
Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3, PKM2
Target/Specificity:
This PKM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the N-terminal region of human PKM2.
Antigen Region:
116-145
Antigen Type: Synthetic Peptide
Gene Name: PKM
Gene ID: 5315
Primary Accession: P14618
NCBI Accession: NP_001193725.1;NP_001193726.1;NP_001193727.1;NP_001193728.1;NP_002645.3;NP_872270.1;NP_872271.1
Other Accession: P11980; P11974; P52480
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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