PKM2 polyclonal, anti-human, mouse, rat

Background:
The PKM2 (pyruvate kinase, muscle) gene encodes the M1- and M2-type isoenzymes through alternative splicing events. Both M1- and M2-type isoforms exists as tetramers and are stimulated by fructose 1,6-bisphosphate. In addition, both isoforms exhibit thyroid hormone binding activity and may be referred to as CTHBP (cytosolic thyroid hormone-binding protein) or THBP1.

Alternative Name:
CTHBP, Cytosolic thyroid hormone binding protein, Cytosolic thyroid hormone-binding protein, KPYM, MGC3932, OIP 3, OIP-3, Oip3, OIP3, OPA interacting protein 3, Opa-interacting protein 3, p58, PK Muscle type, PK, muscle type, PK2, Pk3, PKM, PKM2, PYKM, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Pyruvate kinase muscle isozyme, TCB, THBP1, Thyroid hormone binding protein 1, Thyroid hormone binding protein cytosolic, Thyroid hormone

Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200, IP/RIP: 1:50~1:200

Specificity: PKM2 polyclonal antibody detects endogenous levels of PKM2 protein.

Immunogen:
Recombinant full length Human PKM2.

MW: ~ 58 kDa

Swis Prot.: P14618

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.