PKM2 polyclonal, anti-human, mouse, rat, monkey, rabbit, zebrafish, xenopus
€362.00
In stock
SKU
200122
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Cancers, Carbohydrate Metabolism, Endocrine System, Energy Metabolism, Metabolic Disorders, Nucleotide Metabolism
Description:
PKM2 is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP for generating ATP. There are 4 isoenzymes of pyruvate kinase in mammals (L, R, M1 and M2) encoded by 2 different genes: PKLR and PKM. The L and R isoenzymes are generated from the PKLR by differential splicing of RNA; the M1 and M2 forms are produced from the PKM gene by differential splicing. L type is the major isozyme in liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells. This antibody binds to both M1 and M2 isoforms of PKM.
Alternate Names: Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1, PKM2, PK2, PK3, PKM1, M1-PK, M2-PK
Application Notes: Cat. No. 200122 binds to both M1 and M2 isoforms of PKM. E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P14618, NP_002645
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PKM2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 12.5 % glycerol with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cancers, Carbohydrate Metabolism, Endocrine System, Energy Metabolism, Metabolic Disorders, Nucleotide Metabolism
Description:
PKM2 is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP for generating ATP. There are 4 isoenzymes of pyruvate kinase in mammals (L, R, M1 and M2) encoded by 2 different genes: PKLR and PKM. The L and R isoenzymes are generated from the PKLR by differential splicing of RNA; the M1 and M2 forms are produced from the PKM gene by differential splicing. L type is the major isozyme in liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells. This antibody binds to both M1 and M2 isoforms of PKM.
Alternate Names: Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, Pyruvate kinase 2/3, Cytosolic thyroid hormone-binding protein, CTHBP, THBP1, PKM2, PK2, PK3, PKM1, M1-PK, M2-PK
Application Notes: Cat. No. 200122 binds to both M1 and M2 isoforms of PKM. E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P14618, NP_002645
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PKM2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 12.5 % glycerol with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review