PKM2 polyclonal antibody, anti-human, mouse, rat

Background:
PKM encodes a protein involved in glycolysis. Pyruvate kinase, muscleprovided by is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. Pyruvate kinase, muscleprovided by has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. Pyruvate kinase, muscleprovided by has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of pyruvate kinase, muscleprovided by in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported

Research Area: Signal Transduction, Metabolism

Synonyms: PKM, OIP3, PK2, PK3, PKM2, Pyruvate kinase isozymes M1/M2, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyr

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year