PLA2G15 Polyclonal Antibody

Background:
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction

Synonyms:
1 O acylceramide synthase, 1-O-acylceramide synthase, ACS, DKFZp564A0122, Group XV phospholipase A2, GXVPLA 2, GXVPLA2, LCAT like lysophospholipase, LCAT-like lysophospholipase, LLPL, LPLA 2, LPLA2, LYPLA 3, Lysophospholipase 3 (lysosomal phospholipase A2), Lysophospholipase 3, Lysosomal phospholipase A2, OTTHUMP00000174859, PAG15, Phospholipase A2, group XV, PLA2G15, UNQ341/PRO540

Immunogen: Fusion protein of human PLA2G15

Swissprot: Q8NCC3
Gene Accession: BC011640

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.