PLA2G1B Polyclonal Antibody

Background:
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.

Synonyms:
PLA2G1B, PLA2, PLA2A, PPLA2

Immunogen: Recombinant fusion protein of human PLA2G1B (NP_000919.1).

Swissprot: P04054
Gene ID: 5319

Calculated MW: 16 kDa
Observed MW: 16 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:100-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.