PLA2G2A Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
GIIC sPLA2, Group IIA phospholipase A2, membrane associated, MOM1, Non-pancreatic secretory phospholipase A2, NPS-PLA2, OTTHUMP00000002786, PA2GA, Phosphatidylcholine 2-acylhydrolase 2A, Phospholipase A2, Phospholipase A2 group IIA, Phospholipase A2, group IIA (platelets, synovial fluid), PLA2, PLA2B, PLA2G2A, PLA2L, PLA2S, PLAS1, RASF A, sPLA2

Immunogen: Fusion protein of human PLA2G2A

Swissprot: P14555
Gene Accession: BC005919

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.