PLAG1 antibody (M02) (3B7), anti-human
€375.00
In stock
SKU
AC-AT3333a
Background:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
Isotype: mouse IgG2a Kappa
Other Names:
Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1
Antigen Type: Recombinant Protein
Target/Specificity:
PLAG1 (NP_002646, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Gene Description: pleiomorphic adenoma gene 1
Gene Summary:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Primary Accession: Q6DJT9
Other Accession: NM_002655
Org Accession: NP_002646
NCBI Accession: NP_001108106.1;NP_001108107.1;NP_002646.2
Gene ID: 5324
Gene Name: PLAG1
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Bio References:
1.miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM.Blood. 2009 Oct 8;114(15):3255-64. Epub 2009 Aug 19.
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
Isotype: mouse IgG2a Kappa
Other Names:
Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1
Antigen Type: Recombinant Protein
Target/Specificity:
PLAG1 (NP_002646, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Gene Description: pleiomorphic adenoma gene 1
Gene Summary:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Primary Accession: Q6DJT9
Other Accession: NM_002655
Org Accession: NP_002646
NCBI Accession: NP_001108106.1;NP_001108107.1;NP_002646.2
Gene ID: 5324
Gene Name: PLAG1
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Bio References:
1.miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM.Blood. 2009 Oct 8;114(15):3255-64. Epub 2009 Aug 19.
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