PLAG1 Polyclonal Antibody

Background:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
COL1A2/PLAG1 fusion, FGFR1/PLAG1 fusion variant 3, Plag1, PLAG1, Pleiomorphic adenoma gene 1, Pleiomorphic adenoma gene 1 protein, PSA , SGPA , Zinc finger protein PLAG1, ZNF912

Immunogen: Synthetic peptide of human PLAG1

Swissprot: Q6DJT9
Gene Accession: NP001108106

Calculated MW: 56 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.