Plasma Cells [clone LIV3G11 (7B18)], anti-human

Description: Plasma cells, which are large lymphocytes derived from an antigen-specific B-cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B-cells upon stimulation by CD4+ lymphocytes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This antibody superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this antibody is not suitable for staining frozen tissues.Localization: cytoplasmDilution: 100-500Positive Control: tonsil, lymph nodeHIER: citrate pH6.0 or EDTA pH8.0Status: RUO