PLCB2 Polyclonal Antibody

Background:
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to the second messengers inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

Research Area: Metabolism, Signal transduction

Synonyms:
1-phosphatidylinositol-4, 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-2, 5-bisphosphate phosphodiesterase beta-2, FLJ38135, Phosphoinositide phospholipase C-beta-2, Phospholipase C-beta-2, PLC-beta-2, Plcb2, PLCB2

Immunogen: Fusion protein of human PLCB2

Swissprot: Q00722
Gene Accession: BC000939

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.02 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.