PLCG2 (clone 3A8B6), anti-human
€0.00
In stock
SKU
BT-MCA2036
Catalog Number: BT-MCA2036
Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity: human
Application(s): WB, ICC, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity: human
Application(s): WB, ICC, FCM
Datasheet
Request Information
Background:
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Research Area: Cardiovascular
Synonyms: FCAS3, APLAID, PLC-IV, PLC-gamma-2
Immunogen: Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2(cERDINSLpYDVSRMYV)).
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage:
4°C|-20°C for long term storage
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Research Area: Cardiovascular
Synonyms: FCAS3, APLAID, PLC-IV, PLC-gamma-2
Immunogen: Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2(cERDINSLpYDVSRMYV)).
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage:
4°C|-20°C for long term storage
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