PLD1 polyclonal, anti-human, mouse

Quantity: 100 µg

Background:
By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

Description:
Rabbit IgG polyclonal antibody for Phospholipase D1 (PLD1) detection. Tested with WB in Human, Mouse.

Synonyms:
Choline phosphatase 1 antibody, hPLD 1 antibody, hPLD1 antibody, Human ARF activated phosphatidylcholine specific phospholipase D1a antibody, Phosphatidylcholine hydrolyzing phospholipase D1 antibody, Phosphatidylcholine-hydrolyzing phospholipase D1 antibody, Phospholipase D1 antibody, Phospholipase D1 phosphatidylcholine specific antibody, PhospholipaseD1 antibody, PL D1 antibody, PLD 1 antibody, PLD1 antibody, PLD1_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.