PLEC Polyclonal Antibody

Background:
Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes.

Research Area: Signal transduction

Synonyms:
EBS1, EBSO, HD1, Hemidesmosomal protein 1, PCN, pleC, PLEC, PLEC1, PLEC1b, Plectin 1, Plectin 1 intermediate filament binding protein 500kDa, Plectin 6, Plectin, Plectin-1, PLTN

Immunogen: Synthetic peptide of human PLEC

Swissprot: Q15149
Gene Accession: NP_000436

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7572/sc-28267