Pleiotrophin polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Pleiotrophin(PTN) also known as heparin-binding brain mitogen(HBBM) or heparin-binding growth factor 8(HBGF-8) or neurite growth-promoting factor 1(NEGF1) or heparin affinity regulatory peptide(HARP) or heparin binding growth associated molecule(HB-GAM) is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.

Description:
Rabbit IgG polyclonal antibody for Pleiotrophin (PTN) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
HARP antibody, HB-GAM antibody, HBBM antibody, HBGAM antibody, HBGF-8 antibody, HBGF8 antibody, HBNF antibody, HBNF-1 antibody, HBNF1 antibody, Heparin binding growth associated molecule antibody, Heparin binding growth factor 8 antibody, Heparin binding neurite outgrowth promoting factor 1 antibody, Heparin-binding brain mitogen antibody, Heparin-binding growth factor 8 antibody, Heparin-binding growth-associated molecule antibody, Heparin-binding neurite outgrowth-promoting factor 1 antibody, NEGF1 antibody, Neurite growth promoting factor 1 antibody, OSF-1 antibody, OSF1 antibody, Osteoblast-specific factor 1 antibody, Pleiotrophin antibody, PTN antibody, PTN_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Pleiotrophin(150-168aa QAESKKKKKEGKKQEKMLD), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human Pleiotrophin(150-168aa QAESKKKKKEGKKQEKMLD), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.