PLEKHA1 Polyclonal Antibody

Background:
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3, 4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

Research Area: Signal transduction

Synonyms:
OTTHUMP00000020651, PH domain containing family A member 1, PH domain-containing family A member 1, PKHA1, Pleckstrin homology domain containing A1, Pleckstrin homology domain containing family A member 1, Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member, Pleckstrin homology domain-containing family A member 1, PLEKHA1, Tandem PH domain containing protein 1, Tandem PH domain-containing protein 1, TAPP 1, TAPP-1, TAPP1

Immunogen: Fusion protein of human PLEKHA1

Swissprot: Q9HB21
Gene Accession: BC001136

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.