PLEKHO1 polyclonal, anti-human, mouse, rat

Background:
Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by thePLEKHO1 gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.

Synonyms: OC120, CKIP-1, RP11-458I7.3

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human PLEKHO1

Gene Symbol: PLEKHO1

Gene ID: 51177

Swiss prot: Q53GL0

Calculated MW: 46kDa

Recommended dilution:
WB 1:200-1000, IHC 1:20-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.