PLEKHO1 Polyclonal Antibody

Background:
Pleckstrin homology domain-containing family O member 1is aproteinthat in humans is encoded by thePLEKHO1gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.

Research Area: Signal Transduction

Synonyms:
C-Jun-binding protein, Casein kinase 2-interacting protein 1, CK2 interacting protein 1, CK2 interacting protein 1 HQ0024c protein, CK2-interacting protein 1, CKIP 1, CKIP-1, CKIP1, JBP, OC120, Osteoclast maturation associated gene 120 protein, Osteoclast maturation-associated gene 120 protein, PH domain-containing family O member 1, PKHO1, Pleckstrin homology domain containing family O member 1, Pleckstrin homology domain-containing family O member 1, PLEKHO1

Immunogen: Recombinant protein of human PLEKHO1

Swissprot: Q53GL0
Gene Accession: BC010149

Calculated MW: 46 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-50225/sc-50226/sc-50227