Plexin A1 polyclonal, anti-human, mouse, rat

Background:
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Alternative Name:
PLXNA1, NOV, PLXN1, NOV, NOV/plexin A1 protein, NOVP, Plexin-A1, Plexin1, PlexinA1, PLXA1, PLXN1, Plxna1, PLXNA1 protein, Semaphorin receptor NOV,

Application Dilution:
WB:1:500
ICC:1:50-1:200
FC:1:50-1:100

Specificity: Plexin A1 polyclonal antibody detects endogenous levels of Plexin A1 protein.

Immunogen:
Recombinant protein

MW: 211 kDa

Swiss-Prot: Q9UIW2(Human) P70206(Mouse)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.