PLK-1 (Thr210) polyclonal, anti-mouse , rat, bovine, dog, monkey, xenopys, zebrafish
€536.00
In stock
SKU
252572
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Cell Growth and Death, Endocrine System
Description:
Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles.Deregulated expression of PLK’s is detected in many types of cancer and associated with oncogenesis. It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210.
Alternate Names: Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13, PLK1, PLK
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P53350
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr210 of rat polo-like kinase.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cell Growth and Death, Endocrine System
Description:
Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles.Deregulated expression of PLK’s is detected in many types of cancer and associated with oncogenesis. It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210.
Alternate Names: Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13, PLK1, PLK
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P53350
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr210 of rat polo-like kinase.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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