PLK2 (SNK) Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP7252a
Background:
Plks (polo-like kinases) encode serine/threonine kinases that are closelyrelated to polo and CDC5, genes that are required for passage through mitosisin Drosophila and Saccharomyces, respectively. Polo-like kinases, whichinclude Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cellproliferation. Plk protein accumulates in the cell during S and G2 phases ofthe cell cycle, and both protein content and catalytic activity peak at theonset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk areimmediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
Other Names:
Serine/threonine-protein kinase PLK2, Polo-like kinase 2, PLK-2, hPlk2, Serine/threonine-protein kinase SNK, hSNK, Serum-inducible kinase, PLK2, SNK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7252a was selected from the C-term region of human SNK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PLK2
Gene ID: 10769
Primary Accession: Q9NYY3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Plks (polo-like kinases) encode serine/threonine kinases that are closelyrelated to polo and CDC5, genes that are required for passage through mitosisin Drosophila and Saccharomyces, respectively. Polo-like kinases, whichinclude Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cellproliferation. Plk protein accumulates in the cell during S and G2 phases ofthe cell cycle, and both protein content and catalytic activity peak at theonset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk areimmediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
Other Names:
Serine/threonine-protein kinase PLK2, Polo-like kinase 2, PLK-2, hPlk2, Serine/threonine-protein kinase SNK, hSNK, Serum-inducible kinase, PLK2, SNK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7252a was selected from the C-term region of human SNK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PLK2
Gene ID: 10769
Primary Accession: Q9NYY3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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