PLN Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP20550a
Background:
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2 Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
Other Names:
Cardiac phospholamban, PLB, PLN, PLB
Target/Specificity:
The synthetic peptide sequence is selected from aa 8-22 of HUMAN PLN
Gene Name: PLN (HGNC:9080)
Gene ID: 5350
Primary Accession: P26678
Other Accession: P61016; P61015; P61013; P61014; A4IFH6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2 Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
Other Names:
Cardiac phospholamban, PLB, PLN, PLB
Target/Specificity:
The synthetic peptide sequence is selected from aa 8-22 of HUMAN PLN
Gene Name: PLN (HGNC:9080)
Gene ID: 5350
Primary Accession: P26678
Other Accession: P61016; P61015; P61013; P61014; A4IFH6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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