PLN polyclonal (N-term), anti-human
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In stock
SKU
AC-AP20550a
Catalog Number: AC-AP20550a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB44799
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB44799
Applications: WB
Datasheet
Request Information
Background:
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2 Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
Other Names:
Cardiac phospholamban, PLB, PLN, PLB
Target/Specificity:
This PLN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-22 amino acids from the N-terminal region of human PLN.
Antigen Type: Synthetic Peptide
Gene Name: PLN (HGNC:9080)
Gene ID: 5350
Primary Accession: P26678
Other Accession: P61016; P61015; P61013; P61014; A4IFH6
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2 Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
Other Names:
Cardiac phospholamban, PLB, PLN, PLB
Target/Specificity:
This PLN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-22 amino acids from the N-terminal region of human PLN.
Antigen Type: Synthetic Peptide
Gene Name: PLN (HGNC:9080)
Gene ID: 5350
Primary Accession: P26678
Other Accession: P61016; P61015; P61013; P61014; A4IFH6
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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