PLOD1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS70992
Background:
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity.
Alternative Name:
LH, LH1, LLH, EDS6, PLOD,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: PLOD1 polyclonal antibody detects endogenous levels of PLOD1 protein.
Immunogen:
Recombinant protein of human PLOD1.
MW: ~ 84 kDa
Swis Prot.: Q02809
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity.
Alternative Name:
LH, LH1, LLH, EDS6, PLOD,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: PLOD1 polyclonal antibody detects endogenous levels of PLOD1 protein.
Immunogen:
Recombinant protein of human PLOD1.
MW: ~ 84 kDa
Swis Prot.: Q02809
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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