PLOD1 polyclonal (N-term), anti-human

PLOD1 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP12656c
Catalog Number: AC-AP12656c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30211
Applications: WB, IHC-P, FC
Datasheet

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Background:
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity.

Other Names:
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1, Lysyl hydroxylase 1, LH1, PLOD1, LLH, PLOD

Target/Specificity:
This PLOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human PLOD1.

Antigen Region:
66-94

Antigen Type: Synthetic Peptide

Gene Name: PLOD1
Gene ID: 5351
Primary Accession: Q02809
NCBI Accession: NP_000293.2
Other Accession: Q9R0E2; NP_000293.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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