PLPP1 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Lipid phosphate phosphohydrolase 1, Lipid phosphate phosphohydrolase 1a, LLP1a, LPP1, LPP1, PAP 2a, PAP-2a, PAP2, PAP2-alpha, PAP2a, PAP2a2, PAP2alpha2, PAPalpha1, Phosphatidate phosphohydrolase type 2a, Phosphatidic acid phosphatase 2a, Phosphatidic acid phosphatase type 2A, Phosphatidic acid phosphohydrolase type 2a, PPAP2A, Type 2 phosphatidic acid phosphatase alpha, Type 2 phosphatidic acid phosphohydrolase

Immunogen: Synthetic peptide of human PPAP2A

Swissprot: O14494
Gene Accession: NP_003702

Calculated MW: 32 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.