PLSCR3 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71668
Background:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Alternative Name:
Phospholipid scramblase 3, PL scramblase 3
Application Dilution: WB : 1:500 - 1:2000
Specificity: PLSCR3 polyclonal antibody detects endogenous levels of PLSCR3 protein.
Immunogen:
Recombinant protein of human PLSCR3
MW: Predicted band size: 32 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9NRY6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Alternative Name:
Phospholipid scramblase 3, PL scramblase 3
Application Dilution: WB : 1:500 - 1:2000
Specificity: PLSCR3 polyclonal antibody detects endogenous levels of PLSCR3 protein.
Immunogen:
Recombinant protein of human PLSCR3
MW: Predicted band size: 32 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9NRY6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review