PLXNA4 polyclonal, anti-mouse, rat
€305.00
In stock
SKU
BS60789
Background:
Plexin-A4, also known as PLXNA4 or FAYV2820, is a 1,894 amino acid singlepass type I membrane protein that contains one sema domain, three PSI domains and four IPT/TIG domains. Belonging to a large family of semaphorin (SEMA) receptors, plexin-A4 forms a complex with neuropilin and, once complexed, can propagate SEMA3A-induced inhibitory signals into neurons and cells, possibly playing a role in early nerve development. Four isoforms of plexin-A4 exist due to alternative splicing events. The gene encoding plexin-A4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
Plexin-A4, PLXNA4, KIAA1550, PLXNA4A, PLXNA4B, UNQ2820, PRO34003
Application Dilution: WB: 1:500~1:1000
Specificity: PLXNA4 polyclonal antibody detects endogenous levels of PLXNA4 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human PLXNA4.
MW: ~ 212 kDa
Swis Prot.: Q9HCM2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Plexin-A4, also known as PLXNA4 or FAYV2820, is a 1,894 amino acid singlepass type I membrane protein that contains one sema domain, three PSI domains and four IPT/TIG domains. Belonging to a large family of semaphorin (SEMA) receptors, plexin-A4 forms a complex with neuropilin and, once complexed, can propagate SEMA3A-induced inhibitory signals into neurons and cells, possibly playing a role in early nerve development. Four isoforms of plexin-A4 exist due to alternative splicing events. The gene encoding plexin-A4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
Alternative Name:
Plexin-A4, PLXNA4, KIAA1550, PLXNA4A, PLXNA4B, UNQ2820, PRO34003
Application Dilution: WB: 1:500~1:1000
Specificity: PLXNA4 polyclonal antibody detects endogenous levels of PLXNA4 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human PLXNA4.
MW: ~ 212 kDa
Swis Prot.: Q9HCM2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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