PLXNA4 Polyclonal Antibody

Background:
Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Research Area: Cancer, Neuroscience

Synonyms:
FAYV2820, KIAA1550, PLEXA4, Plexin-A4, PlexinA4, PLXA4, plxna4, PLXNA4A, PLXNA4B, PRO34003, UNQ2820/PRO34003

Immunogen: Synthetic peptide of human PLXNA4

Swissprot: Q9HCM2
Gene Accession: NP_001099013

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.