PML Peptide
€100.00
In stock
SKU
350546
Protein Family: Transcription Factors, Ubiquitins
Pathway and Disease: Cancers, Folding, Sorting and Degradation, Transcription
Alternate Names: Probable transcription factor PML; Tripartite motif-containing protein 19; RING finger protein 71; PML; MYL; RNF71; TRIM19; Promyelocytic leukemia protein
Accession No.: P29590, NP_150241
Description:
Promyelocytic leukemia protein (PML) is a transcription factor involved in transcriptional regulation and nuclear protein sequestration, such as recruiting ELF4 into PML nuclear bodies. A chromosomal aberration involving PML is a cause of acute promyelocytic leukemia.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 1963.1 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200184 is selected from a sequence within the N-term region of human PML. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C80H131N29O27S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Cancers, Folding, Sorting and Degradation, Transcription
Alternate Names: Probable transcription factor PML; Tripartite motif-containing protein 19; RING finger protein 71; PML; MYL; RNF71; TRIM19; Promyelocytic leukemia protein
Accession No.: P29590, NP_150241
Description:
Promyelocytic leukemia protein (PML) is a transcription factor involved in transcriptional regulation and nuclear protein sequestration, such as recruiting ELF4 into PML nuclear bodies. A chromosomal aberration involving PML is a cause of acute promyelocytic leukemia.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 1963.1 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200184 is selected from a sequence within the N-term region of human PML. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C80H131N29O27S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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