PML polyclonal, anti-human, monkey
€362.00
In stock
SKU
200184
Protein Family: Transcription Factors, Ubiquitins
Pathway and Disease: Cancers, Folding, Sorting and Degradation, Transcription
Description:
Promyelocytic leukemia protein (PML) is a transcription factor involved in transcriptional regulation and nuclear protein sequestration, such as recruiting ELF4 into PML nuclear bodies. A chromosomal aberration involving PML is a cause of acute promyelocytic leukemia.
Alternate Names: Probable transcription factor PML, Tripartite motif-containing protein 19, RING finger protein 71, PML, MYL, RNF71, TRIM19, Promyelocytic leukemia protein
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P29590, NP_150241
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PML.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Kolegraff K et al. 2011. Molecular Biology of the Cell. 22: 1121-1134. PMID# 21325624.
[2] Schnoor M et al. 2009. Mucosal Immnology. 2:33-42. PMID# 19079332.
Pathway and Disease: Cancers, Folding, Sorting and Degradation, Transcription
Description:
Promyelocytic leukemia protein (PML) is a transcription factor involved in transcriptional regulation and nuclear protein sequestration, such as recruiting ELF4 into PML nuclear bodies. A chromosomal aberration involving PML is a cause of acute promyelocytic leukemia.
Alternate Names: Probable transcription factor PML, Tripartite motif-containing protein 19, RING finger protein 71, PML, MYL, RNF71, TRIM19, Promyelocytic leukemia protein
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P29590, NP_150241
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PML.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Kolegraff K et al. 2011. Molecular Biology of the Cell. 22: 1121-1134. PMID# 21325624.
[2] Schnoor M et al. 2009. Mucosal Immnology. 2:33-42. PMID# 19079332.
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