PMM2 Polyclonal Antibody

Background:
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Research Area: Metabolism, Signal Transduction

Synonyms:
PMM2, CDG1, CDG1a, CDGS, PMI, PMI1, PMM 2

Immunogen: Recombinant fusion protein of human PMM2 (NP_000294.1).

Swissprot: O15305
Gene ID: 5373

Calculated MW: 13 kDa/28 kDa
Observed MW: 28 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.