PMP-22 polyclonal, anti-human, mouse, rat, chimpanzee, monkey, rabbit

Protein Family: Receptors and Channels

Pathway and Disease: Cell Growth and Death, Nervous and Sensory Systems, Neurodegenerative Disorders

Description:
Peripheral myelin protein 22 (PMP-22) is an integral membrane protein involved in growth regulation and myelinization in the peripheral nervous system. PMP-22 is found in the tumors of Schwann cell lineage where axons are present (neurofibromas) but not where axons are absent (schwannomas). Defects in PMP22 are the cause of hereditary motor and sensory neuropathies, including Charcot-Marie-Tooth disease type 1A and Dejerine-Sottas syndrome.

Alternate Names: Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, PMP22, GAS3

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: Q01453

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PMP-22.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.