PMPCA polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71389
Background:
PMPCA (peptidase (mitochondrial processing) alpha), also known as alpha-MPP, P-55, INPP5E or MPPA, is a 525 amino acid protein that belongs to the peptidase M16 family and exists as a heterodimer of alpha and beta subunits. Localizing to mitochondrial matrix, PMPCA cleaves transit peptides from mitochondrial protein precursors. PMPCA is encoded by a gene that maps to human chromosome 9 , which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Alternative Name:
INPP5E, KIAA0123, MPPA, Alpha-MPP, P-55, α-MPP, MPP-α, MPPα,
Application Dilution: WB: 1:500 - 1:2000
Specificity: PMPCA polyclonal antibody detects endogenous levels of PMPCA protein.
Immunogen:
Recombinant protein of human PMPCA.
MW: ~ 58 kDa
Swis Prot.: Q10713
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
PMPCA (peptidase (mitochondrial processing) alpha), also known as alpha-MPP, P-55, INPP5E or MPPA, is a 525 amino acid protein that belongs to the peptidase M16 family and exists as a heterodimer of alpha and beta subunits. Localizing to mitochondrial matrix, PMPCA cleaves transit peptides from mitochondrial protein precursors. PMPCA is encoded by a gene that maps to human chromosome 9 , which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Alternative Name:
INPP5E, KIAA0123, MPPA, Alpha-MPP, P-55, α-MPP, MPP-α, MPPα,
Application Dilution: WB: 1:500 - 1:2000
Specificity: PMPCA polyclonal antibody detects endogenous levels of PMPCA protein.
Immunogen:
Recombinant protein of human PMPCA.
MW: ~ 58 kDa
Swis Prot.: Q10713
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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