PMS2 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7356b
Background:
PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in PMS2 gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.
Other Names:
Mismatch repair endonuclease PMS2, 31--, DNA mismatch repair protein PMS2, PMS1 protein homolog 2, PMS2, PMSL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7356b was selected from the C-term region of human PMS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PMS2 (HGNC:9122)
Gene ID: 5395
Primary Accession: P54278
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in PMS2 gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.
Other Names:
Mismatch repair endonuclease PMS2, 31--, DNA mismatch repair protein PMS2, PMS1 protein homolog 2, PMS2, PMSL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7356b was selected from the C-term region of human PMS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PMS2 (HGNC:9122)
Gene ID: 5395
Primary Accession: P54278
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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