PMS2 antibody (clone 4G4), anti-human

Background:
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

Other Names:
Mismatch repair endonuclease PMS2, 31--, DNA mismatch repair protein PMS2, PMS1 protein homolog 2, PMS2, PMSL2

Antigen Type:
Recombinant Protein

Gene Name: PMS2 (HGNC:9122)
Gene ID: 5395
NCBI Accession: NP_000526.1
Primary Accession: P54278
Other Accession: NM_000535
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .