PMVK Polyclonal Antibody

Background:
This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.

Research Area: Cancer,Metabolism,Signal Transduction

Synonyms:
PMVK, HUMPMKI, PMK, PMKA, PMKASE, POROK1

Immunogen: Recombinant fusion protein of human PMVK (NP_006547.1).

Swissprot: Q15126
Gene ID: 10654

Calculated MW: 21 kDa
Observed MW: 22 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.