PNK1 (Phospho-Ser114/Thr118) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage| the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly| seizures| and developmental delay.

Research Area: Epigenetics and nuclear signaling

Synonyms: PNK1 , Ser114/Thr118, Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase [Includes: Polynucleotide 3'-phosphatase, EC 3.1.3.32, 2', 3'-polynucleotidase, Polynucleotide 5'-hydroxyl-kinase, EC 2.7.1.78,

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year