PNKP Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14116a
Background:
This locus represents a gene involved in DNA repair. Inresponse to ionizing radiation or oxidative damage, the proteinencoded by this locus catalyzes 5' phosphorylation and 3'dephosphorylation of nucleic acids. Mutations at this locus havebeen associated with microcephaly, seizures, and developmentaldelay.
Other Names:
Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase, Polynucleotide 3'-phosphatase, 2'(3')-polynucleotidase, Polynucleotide 5'-hydroxyl-kinase, PNKP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14116a was selected from the N-term region of PNKP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PNKP {ECO:0000303|PubMed:10446192, ECO:0000312|HGNC:HGNC:9154}
Gene ID: 11284
Primary Accession: Q96T60
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This locus represents a gene involved in DNA repair. Inresponse to ionizing radiation or oxidative damage, the proteinencoded by this locus catalyzes 5' phosphorylation and 3'dephosphorylation of nucleic acids. Mutations at this locus havebeen associated with microcephaly, seizures, and developmentaldelay.
Other Names:
Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase, Polynucleotide 3'-phosphatase, 2'(3')-polynucleotidase, Polynucleotide 5'-hydroxyl-kinase, PNKP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14116a was selected from the N-term region of PNKP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PNKP {ECO:0000303|PubMed:10446192, ECO:0000312|HGNC:HGNC:9154}
Gene ID: 11284
Primary Accession: Q96T60
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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