PNKP polyclonal antibody, anti-human, mouse, rat

Background:
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Research Area: Epigenetics and nuclear signaling

Synonyms: Bifunctional polynucleotide phosphatase/kinase , DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase [Includes: Polynucleotide 3'-phosphatase , EC 3.1.3.32, 2', 3'-polynucleotidase, P

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year