PNKP Polyclonal Antibody

Background:
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
PNKP, AOA4, EIEE10, MCSZ, PNK

Immunogen: Recombinant fusion protein of human PNKP (NP_009185.2).

Swissprot: Q96T60
Gene ID: 11284

Calculated MW: 53 kDa/57 kDa
Observed MW: 57 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.